The Sol Goldman Pancreatic Cancer Research Center

What's New 2012

Gift to Sequence DNA of 500 people

The Sol Goldman Pancreatic Cancer Center has received a generous gift to sequence the DNA (genomes) of over 500 people with familial pancreatic cancer. A wonderful example of the impact philanthropy can have, this unique gift will allow scientists at the Goldman Center to define all of the most common inherited DNA changes that predispose to pancreatic cancer. It is hoped that this understanding will, in turn, allow clinicians to predict more accurately a person's risk of developing pancreatic cancer, and that some of the changes will lead to gene-specific treatments for patients who develop pancreatic cancer.

The team at Hopkins has reached out to other centers across North America, and these collaborating centers will contribute samples from research subjects at their institutions. The team at Johns Hopkins is also committed to sharing data generated by this study with other pancreatic cancer scientists, so that the entire research community can benefit from this landmark undertaking. Learn more about familial pancreatic cancer visit and how you can support pancreatic cancer research at Johns Hopkins.


Congratulations Dr. Hanno Matthaei!

Hanno Matthaei
Hanno Matthaei MD in the Sol Goldman Pancreatic Cancer Research Center received the "Ferdinand Sauerbruch Research Award" from the Surgical Society of Berlin in a ceremony in Berlin Germany. This 5,000 Euro prize is awarded by the Society for outstanding research by a young surgeon. Dr. Matthaei received this prestigious award for work he conducted in the laboratory of Dr. Anirban Maitra on the molecular pathogenesis and diagnostics of intraductal papillary mucinous neoplasms of the pancreas. Congratulations Hanno!



Congratulations to the pancreatic cancer team at Johns Hopkins!

top Docs coverThirteen doctors in the Sol Goldman Pancreatic Cancer Research Center were selected by Castle Connolly as Washington-Baltimore "top doctors." They include John Cameron, Marcia Canto, Michael Choti, Elliot Fishman, Deborah Frassica, Michael Goggins, Ralph Hruban, Scott Kern, Daniel Laheru, Steven Leach, Anirban Maitra, Timothy Pawlik, and Ross Donehower. To learn more login to: TopDoctorsWashington-Baltimore.com




Fifteen-Year-Old Wins Award

Dr. AliFifteen-year-old Jack Andraka of Crownsville won the top prize at the Intel International Science and Engineering Fair for designing a new approach to detecting molecules in the blood, Intel announced Friday. Jack has been working in the lab of pancreatic cancer researcher Dr. Anirban Maitra. The top prize is $75,000!



Dr. John L. Cameron performs his 2,000th Whipple

Dr. John L. Cameron, Professor of Surgery at the Johns Hopkins University reached a remarkable milestone. Dr. Cameron performed his 2000th Whipple resection. This milestone not only represents a significant personal accomplishment for Dr. Cameron, but also is a momentous achievement in fight against pancreatic cancer. Dr. Cameron’s work has formed the basis for all of the pancreatic cancer research at Johns Hopkins. In addition, he has trained a generation of surgical residents who themselves have gone out across the country to start their own pancreatic surgery programs. In turn, many of these surgeons have trained additional residents. Dr. Cameron is to be congratulated for reaching this remarkable milestone, and for the lasting legacy he has had providing patients with pancreatic cancer real hope.



Hopkins Team featured in Cell

In the January 20th issue of Cell, Drs. Christine Iacobuzio-Donahue and Joseph Herman from the Sol Goldman Pancreatic Cancer Center, in collaboration with Dr. Franziska Michor at the Dana Farber Cancer Institute, reported on the growth features of pancreatic cancer.

This unique collaboration relied on comprehensive data collected by Dr. Iacobuzio in association with autopsies she performed on patients who died of pancreatic cancer, Dr. Michors expertise in computational modeling of metastasis growth dynamics, and Dr. Herman's expertise in clinical management and treatment of pancreatic cancer patients at Johns Hopkins. First, using data of 101 patients who underwent an autopsy, they characterized the growth dynamics and metastasis of pancreatic cancers and created a mathematical model based on those features. This model was then used to predict a variety of features of pancreatic cancer growth and dissemination in the setting of different treatments, and these findings were then validated in a separate set of 127 patients who had surgery at Johns Hopkins. Together they showed that pancreatic cancers are growing at an accelerated rate when they are diagnosed, that for most patients metastases are already present at diagnosis, and that initiating treatments as soon as possible following diagnosis directly affects patient outcome. The largest implication of their findings is that initiating chemotherapy prior to surgery may offer the greatest chance of survival.


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