The Sol Goldman Pancreatic Cancer Research Center

The National Familial Pancreas Tumor Registry

The NFPTR Team

From left to right: Dr. James Eshleman, Ms. Emily Palmisano, Dr. Ralph Hruban, Dr. Marcia Canto, Dr. Michael Goggins, Dr. Alison Klein, Ms. Jennifer Axilbund, Ms. Marian Raben, Dr. Christine Iacobuzio-Donahue.
From left to right: Dr. James Eshleman, Ms. Emily Palmisano, Dr. Ralph Hruban,
Dr. Marcia Canto, Dr. Michael Goggins, Dr. Alison Klein, Ms. Jennifer Axilbund,
Ms. Marian Raben, Dr. Christine Iacobuzio-Donahue.

The NFPTR team is composed of a talented group of researchers and clinicians who bring with them enthusiasm and a unique approach to studying pancreatic tumors and their precursors. Here is the team:

Dr. Alison P. Klein is Director of the National Familial Pancreas Tumor Registry. She is an Associate Professor of Oncology and Epidemiology with a joint appointment at The Johns Hopkins Bloomberg School of Public Heath. Her research focus is to identify the genes and enviromental factors that cause pancreatic cancer and translate these findings into improved patient care and risk assessment.

Dr. Ralph Hruban is Director of GI/Liver Pathology and Director of The Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins. He is a Professor of Pathology and Oncology. His research focuses on the precursor lesions that give rise to invasive pancreatic cancer. Just as colon polyps can give rise to colon cancer, Dr. Hruban has shown that small precursor lesions in the pancreas can give rise to pancreatic cancer.

Dr. Michael Goggins is a Professor of Pathology and Medicine. His main research focus includes improving the early detection of pancreatic cancer. To this end, he is working to identify new molecular markers for the early detection of pancreatic cancer.

Dr. Jim Eshleman is a Professor of Pathology. He develops new technologies that can be used to detect early pancreatic cancer. For example, Dr. Eshleman developed the LigAmp technology, which is now being evaluated as an early detection test for pancreatic cancer.

Dr. Marcia Canto is a Professor of Medicine. Dr. Canto's efforts focus on screening individuals using endoscopic ultrasound (EUS) that have been shown to have a high risk of developing pancreatic cancer.

Jennifer Axilbund is a genetic counselor who works closely with the National Familial Pancreas Tumor Registry. She not only counsels individuals with a strong family history of pancreatic cancer but is also doing research on how best to counsel these patients.

Dr. Scott Kern is a Professor of Pathology and Oncology. He is interested in fundamental gene discovery and in translating these gene discoveries to better patient care. For example, his current interests include treating pancreatic cancers that arose in patients with BRCA2 gene mutations with a chemotherapeutic agent (mitomycin C) that specifically targets changes caused by BRCA2 gene mutations.

Dr. Joseph Herman is an Associate Professor of Radiation Oncology, Urology, and Surgery and the Director of the Pancreas Multi-Disciplinary Cancer Clinic (PMDC). His primary interests include translational and clinical research, and improving patients' quality of life. He is studying how 4-D and PET-CT scans can be used to better assess treatment response, decrease toxicity, and allow radiation dose escalation.

Dr. Daniel Laheru is a Professor of Oncology. He is very active in the clinical treatment of patients with pancreatic cancer, and he also conducts research on new immunological methods (vaccines) to treat pancreatic cancer.

Dr. Elizabeth Jaffee is a Professor of Oncology. She has developed a vaccine for the treatment of pancreatic cancer. This vaccine is made from the cancer cells themselves.

Dr. John Cameron is a Professor of Surgery and an expert in the field of pancreatic cancer surgery. Dr. Cameron has probably performed more Whipple surgeries (removal of the head of the pancreas) than any other surgeon in the world.

Dr. Martin Makary is an Associate Professor of Surgery and of Health Policy and Management. Dr. Makary specializes in pancreatic cancer, minimally-invasive (laparoscopic) surgery and surgery in the elderly.

Dr. Timothy Pawlik is an Assistant Professor of Surgery. Dr. Pawlik focuses on liver, gallbladder, bile duct, pancreas, and gastrointestinal tumors and cancers and his research includes experimental therapeutics of hepatic malignancies and clinical trials in gastrointestinal malignancies.

Dr. Christopher Wolfgang is an Assistant Professor of Surgery. Dr. Wolfgang's primary clinical interests are cancers and benign disease of the liver, pancreas, bile duct and gallbladder. His major scientific interest is in the biological behavior of pancreatic cancers.

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